HIGHLIGHTS
- who: Jiri Jungwirth from the InstitutCharles University have published the article: Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition, in the Journal: Scientific Reports Scientific Reports of December/31,/2019
- what: The aim of this study was to explore the genetic heterogeneity of adenomas and early carcinomas by analyzing the mutation spectrum of well-known genes involved in colorectal carcinogenesis (APC, BRAF, EGFR, NRAS, KRAS, PIK3CA, POLE, POLD1, SMAD4, PTEN, and TP53) in a large, well-defined series of adenomas and in situ carcinomas with follow up using a next . . .
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