Mycn-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma

HIGHLIGHTS

• who: Ling Tao from the College University of of Medicine, Houston, TX, USA have published the research work: MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show that targeting FA uptake effectively inhibits MYCN-induced glycerolipid accumulation and tumor growth, suggesting that FA transport is critical for these functions. The study shows that MYCN-driven tumors rely heavily on FA uptake for survival, suggesting that FA uptake may represent a promising therapeutic target in high-risk MNA patients.
• how: MYCN . . .
  

   

  

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