Mycobacterium tuberculosis antigens repress th1 immune response suppression and promotes lung cancer metastasis through pd-1/pdl-1 signaling pathway

HIGHLIGHTS

  • who: Shuhui Cao from the Five patients with pulmonary TB were enrolled from the Thoracic hospital affiliated to Shanghai Jiaotong University, which was approved by the Institutional Review Board of the hospitalInformed consent was signed and provided. TB infection was diagnosed on the basis of clinical findings and supporting evidence from ancillary tests such as lung imaging and sputum Gram's staining. Five healthy individuals vaccinated with BCG vaccine for tuberculosis were included as control. Peripheral blood was collected from all subjects to isolate peripheral blood mononuclear cells. All patients received anti-TB treatment after blood draw . . .

     

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