Mycobacterium tuberculosis exploits a molecular off switch of the immune system for intracellular survival

HIGHLIGHTS

  • who: Ulrich von Both from the (UNIVERSITY) have published the research: Mycobacterium tuberculosis Exploits a Molecular Off Switch of the Immune System for Intracellular Survival, in the Journal: (JOURNAL) of 14/03/2017
  • what: The authors show that during infection of human whole blood with M. tuberculosis, host gene transcriptional suppression, rather than activation, is the predominant response. As the in_vitro infection experiment and time course of the Leishmania study were similar to that in the study , the authors were able to directly compare the log2 FC of the 1000 most SDE genes in response . . .

     

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