Mycobacterium tuberculosis senses host interferon-γ via the membrane protein mmpl10

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  • who: Mohamed Ahmed from the College University of Southampton, Southampton , YD, UK have published the Article: Mycobacterium tuberculosis senses host Interferon-u03b3 via the membrane protein MmpL10, in the Journal: (JOURNAL) of 15/Nov/2022
  • what: The authors show that virulent Mtb binds to and exhibits a dose-dependent increase in metabolic activity but is unresponsive to other cytokines tested including __NEWPAGE__ARTICLE Fig 6 promotes Mtb growth via MmpL10. Critically using a 3D granuloma model the authors show that promotes Mtb growth when MmpL10 is present. The authors have demonstrated a hithero unknown effect of . . .

     

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