HIGHLIGHTS
- who: Annabelle Varrot from the (UNIVERSITY) have published the Article: Mycobacterium tuberculosis Strains Possess Functional Cellulases*, in the Journal: (JOURNAL) of March/29,/2005
- what: The authors show that M. tuberculosis H37Rv does indeed possess a functional cellulase. The authors show that it is a functional cellulase that liberates a repertoire of cello-oligosaccharides from acid-swollen cellulose and barley -glucan with an endo action.
SUMMARY
The x-ray crystal_structure of this enzyme, in ligand complex forms, from 1.9 to 1.1Å resolution, reveals a highly conserved substrate-binding cleft . . .
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