HIGHLIGHTS
- who: Minoru Shigesaka from the First Department of Internal Medicine, Kansai Medical University, Shin-machi, Hirakata City, Osaka, Japan have published the Article: Mycophenolic acid, the active form of mycophenolate mofetil, interferes with IRF7 nuclear translocation and type I IFN production by plasmacytoid dendritic cells, in the Journal: (JOURNAL)
- what: The authors focus on the effects of MMF in targeting DC functions especially the response of pDCs. The authors show a novel function of MMF/MPA, i.e., the ability to inhibit IFN-α production by human pDCs upon cellular activation with SLE serum or CpG . . .
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