Mycothiol synthesis by an anomerization reaction through endocyclic cleavage

HIGHLIGHTS

  • who: Shino Manabe and Yukishige Ito from the 51-0198, Japan have published the research work: Mycothiol synthesis by an anomerization reaction through endocyclic cleavage, in the Journal: (JOURNAL)
  • what: We demonstrated a MSH synthesis using an anomerization reaction through endocyclic cleavage in the presence of a weak Lewis acid.

SUMMARY

    Tuberculosis is an infectious disease and has had a high death rate over the past few decades. The conformation of MSH has been investigated by NMR analyses and computational calculations. N-acyl variants of MSH homologs, such as formyl, propanoyl . . .

     

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