Myd88 interacts with interferon regulatory factor (irf) 3 and irf7 in atlantic salmon (salmo salar)

HIGHLIGHTS

  • who: Dimitar B. Iliev from the Dimitar BIliev, Mehrdad Sobhkhez, Kjersti Fremmerlid, and Jorunn B. Jrgensen, From the Faculty of Biosciences, Fisheries and Economics, University of Troms, Troms, Norway Background: My, directly interacts and affects IRF activation in mammals, but no information has been available about lower vertebrates. Results: Transgenic My, interacts with , and IRF A/B and modulates the IRF-induced IFN response and accumulates in aggresomes in Atlantic salmon. Conclusions: My, is involved in the regulation of the IRF-induced IFN response in Atlantic salmon. Significance: The results shed light on the evolution of the . . .

     

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