Myeloid cell-specific ablation of runx2 gene exacerbates post-infarct cardiac remodeling

HIGHLIGHTS

• who: Masashi Tomimatsu from the LaboratoryOsaka University, Suita, Japan have published the research work: Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling, in the Journal: Scientific Reports Scientific Reports
• what: Immunofluorescence staining with anti-Runx2 and anti-periostin (myofibroblast marker) antibodies demonstrated that Runx2 was also expressed in myofibroblasts; however, since the ratio of R u00ad unx2+periostin+ cells to R u00ad unx2+ cells was small, the authors focused on Runx2 which is expressed in myeloid cells. The authors demonstrated that the expression of Runx2 was upregulated in the post-infarct . . .
  

   

  

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