HIGHLIGHTS
- who: Yuze Wu from the (UNIVERSITY) have published the article: Myeloid-derived suppressor cells: an emerging target for anticancer immunotherapy, in the Journal: (JOURNAL)
- what: In this review the authors focus primarily on the classification and inhibitory function of MDSCs and the crosstalk between MDSCs and other myeloid cells. A phase IIa, open-label, two-cohort clinical trial was conducted to assess the safety, efficacy and immunobiological effects of BL-8040, a CXCR4 antagonist.
- how: All these experiments were conducted in_vitro.
SUMMARY
As early as 1978, it was found . . .
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