Myeloid-derived suppressor cells: new insights into the pathogenesis and therapy of mds

HIGHLIGHTS

  • who: Maria Velegraki et al. from the Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center-James, Columbus, OH, USA have published the research: Myeloid-Derived Suppressor Cells: New Insights into the Pathogenesis and Therapy of MDS, in the Journal: (JOURNAL)
  • what: Unfortunately, the trial was prematurely terminated during the dosing escalation phase before reaching the planned maximum dose, as there were no observed hematological responses in other than one patient, who showed a noteworthy increase in their hemoglobin levels . The main reason for the failure of this trial seems to be . . .

     

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