HIGHLIGHTS
- What: Among 180 candidate proteins in the nucleus (Supplementary Data 2), the authors focused on PKM2, a key enzyme that catalyzes the conversion of phosphoenolpyruvate to pyruvate and plays a pivotal role in glycolysis of CRC23. The authors report a novel oncogenic factor MYG1 that drives CRC progression and promotes glycolysis by coordinating nuclear and mitochondrial function.
- Who: Jianxiong Chen from the Animal Care and Use Committee (IACUC) at the Southern Medical University in Guangzhou have published the article: MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration, in the Journal: (JOURNAL) of . . .
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