HIGHLIGHTS
- who: Mohit Kumar et al. from the Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA have published the research: Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy, in the Journal: (JOURNAL) of 29/Nov/2022
- what: The authors investigated the role of myofilaments in R14del-PLN pathology. This work aimed to determine the myofilament properties of cardiomyocytes in both right (RV) and left ventricular (LV) cardiomyocytes from R14del-PLN mice. This study aimed to demonstrate that human R14del-PLN is associated with myofilament dysfunction, potentially one of the underlying cellular mechanisms . . .
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