Myogenesis defects in a patient-derived ipsc model of hereditary gne myopathy

HIGHLIGHTS

  • who: Rebecca E. Schmitt and collaborators from the (UNIVERSITY) have published the research: Myogenesis defects in a patient-derived iPSC model of hereditary GNE myopathy, in the Journal: (JOURNAL)
  • what: The authors report the development of an in_vitro GNE myopathy model using patient-derived induced pluripotent stem_cells (iPSCs).
  • future: Future studies however are needed to confirm this hypothesis and determine the full extent of MRF gene regulation in differentiating iMPCs. npj Regenerative Medicine 48 Despite subtle differences between the mRNA and protein studies both data sets clearly point to substantial deficiencies in myogenic . . .

     

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