Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity

HIGHLIGHTS

  • who: Tingqing Guo and colleagues from the Editor: Jose AL. Calbet, University of Las Palmas de Gran Canaria, Spain have published the research: Myostatin Inhibition in Muscle, but Not Adipose Tissue, Decreases Fat Mass and Improves Insulin Sensitivity, in the Journal: (JOURNAL) of March/19,/2009
  • how: To determine whether Mstn2/2 mice have higher glucose uptake than Mstn+/+ mice the authors carried out a hyperinsulinemic-euglycemic clamp experiment.

SUMMARY

    The Mstn gene is expressed at low levels in adipose_tissue and myostatin protein is found in circulation suggesting that myostatin could . . .

     

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