N-acetyl-l-phenylalanine racemization during tbtu amidation: an in-depth study for the synthesis of anti-inflammatory 2-(n-acetyl)-l-phenylalanylamido-2-deoxy-d-glucose (napa)

HIGHLIGHTS

• who: Elisa Sturabotti et al. from the Department of Chemistry, Sapienza University of Rome, Ple Aldo Moro, Rome, Italy have published the paper: N-Acetyl-l-phenylalanine Racemization during TBTU Amidation: An In-Depth Study for the Synthesis of Anti-Inflammatory 2-(N-Acetyl)-l-phenylalanylamido-2-deoxy-d-glucose (NAPA), in the Journal: Molecules 2023, 28, 581. of /2023/
• what: The TBTU coupling agent was tested to obtain the optically pure bioactive compound NAPA from the reaction of N-acetyl-L-phenylalanine with 1,3,4,6-tetra-Oacetyl-u03b2-D-glucosamine, maintaining the . . .
  

   

  

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