N-acyl-o-phosphocholineserines: structures of a novel class of lipids that are biomarkers for niemann-pick c1 disease

HIGHLIGHTS

• who: Rohini Sidhu from the DepartmentsWashington University have published the Article: N-acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease, in the Journal: (JOURNAL)
• what: The authors identified the structure of lysoSM-509 by accurate mass measurements, tandem mass spectra, chemical derivatization, and comparison to an authentic synthetic standard. Although the effort to elucidate the biosynthesis of APCS using blood drying on newborn screening cards in this study was not successful, the work has eliminated a number of possibilities and provided a foundation for future . . .
  

   

  

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