N-glycans differentially regulate eosinophil and neutrophil recruitment during allergic airway inflammation*

HIGHLIGHTS

  • who: Nooshin S. Bahaie from the EXPERIMENTAL PROCEDURES Mouse Model of Allergic Airway Inflammation-Mgat5u2afa/u2afa mice on a C BL/, background were obtained from the Consortium for Functional Glycomics and bred in-houseOffspring were genotyped by PCR using genomic DNA isolated from tail clippings. Age- and gender-matched Mgat5u2afa/u2afa and WT C BL/, mice were sensitized with , u242eg of ovalbumin (OVA, Grade V, Sigma) in , mg of aluminum hydroxide gel intraperitoneally. Control mice received aluminum hydroxide gel alone. Sixteen days later, control and OVA-sensitized mice were exposed to aerosolized saline alone or OVA in . . .

     

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