HIGHLIGHTS
SUMMARY
The gut microbiota community is important for health, as an imbalance in the microbiota population correlates with some diseases. The authors discovered that the host N-glycosylation protein BCF-1, activated by the gut E. coli, promotes E. coli colonization by directly binding bacteria. The authors identified that OSTB-1, a glucosyltransferase, interacts with BCF-1 for regulating its N-glycosylation, emphasizing that N-glycosylation is critical for E. coli binding and colonization. As there is less E. coli colonization in young larval animals, the authors next questioned if BCF-1 also affects E . . .
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