N-hydroxy-n-propargylamide derivatives of ferulic acid: inhibitors of cholinesterases and monoamine oxidases

HIGHLIGHTS

  • who: u00d3scar M. Bautista-Aguilera and collaborators from the Universidad de Alcalu00e1, Departamento de Quu00edmica Orgu00e1nica y Quu00edmica Inorgu00e1nica, Ctra, Madrid-Barcelona Km, Alcalu00e1 de Henares, Madrid, Spain have published the paper: N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases, in the Journal: Molecules 2022, 27, x FOR PEER REVIEW of 27/Oct/2022
  • what: AD is a neurodegenerative disorder and the most common form of senile dementia.
  • how: The structure of hAChE crystallized with fasciculin II (PDB ID 1B41) was used and docking of compound 4 . . .

     

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