Na /h -exchanger 1 enhances antitumor activity of engineered nk-92 natural killer cells

HIGHLIGHTS

• who: Steven M. Albelda and colleagues from the Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA have published the research work: Na /H -exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells, in the Journal: (JOURNAL) of 02/08/2022
• what: The authors focused on metabolically engineering immune effector cells as an alternative approach to specifically mitigate the inhibitory effect of the acidic TME on immune effector cells. Among the human melanoma cell lines tested, the authors focused on WM3629, an NK-92-sensitive . . .
  

   

  

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