Nad salvage pathway machinery expression in normal and glaucomatous retina and optic nerve

HIGHLIGHTS

  • who: James R. Tribble from the (UNIVERSITY) have published the article: NAD salvage pathway machinery expression in normal and glaucomatous retina and optic nerve, in the Journal: (JOURNAL)
  • what: The authors compare this to protein expression by utilizing highly preserved enucleated eyes from St. Eriks Eye Hospital, Stockholm (i.e. from living donors having their eye removed due to painful glaucoma not post mortem tissue, and corresponding controls). The authors demonstrate that the inner retina is well-endowed with the enzymatic machinery to utilize nicotinamide directly, and identify changes in this expression profile in severe . . .

     

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