HIGHLIGHTS
- who: from the Laboratory findings have published the paper: Naiu0308ve B cells followed by aquaporin-4 antibodies characterise the onset of neuromyelitis optica: evidence from stem cell transplantation, in the Journal: (JOURNAL)
- what: By detailing a case with an early, severe neurological complication after stem_cell transplantation, the authors provide an opportunity to observe in_vivo the development of AQP4 antibodies.
SUMMARY
Neuromyelitis_optica spectrum disorders (NMOSDs) are mediated by antibodies directed against the extracellular domain of aquaporin-4 (AQP4). The immunological mechanisms underlying the generation of AQP4 antibodies during disease initiation are incompletely . . .
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