Naja mossambica mossambica cobra cardiotoxin targets mitochondria to disrupt mitochondrial membrane structure and function

HIGHLIGHTS

  • who: Boris Zhang and colleagues from the University of Nevada, Reno School of Medicine, Department of Pharmacology, Reno, NV, USA have published the article: Naja mossambica mossambica Cobra Cardiotoxin Targets Mitochondria to Disrupt Mitochondrial Membrane Structure and Function, in the Journal: (JOURNAL) of January/18,/2019
  • what: The authors show that the same two cytotoxins (CTI and CTII) induce the formation of a transient non-bilayer phase in mitochondrial membranes at very low concentrations, a phenomenon that leads to increased ATP synthase activity . The authors show that cardiotoxin VII4, an S-type cardiotoxin that possesses . . .

     

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