Nampt encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a “one-stone-two-birds” manner

HIGHLIGHTS

• who: Guanghao Wu from the The procedures of animal experiments were approved by the Institutional Animal Care and Use Committee of Tongji UniversityYoung (, months, weight, g) and old (, months, weight, g) C BL/, J mice were obtained from Vital River Laboratory Animal Technology Co [, ]. Ltd. (Beijing, China). At least one week of acclimation was allowed before advanced experiments. The mice were raised under specific pathogen-free (SPF) conditions with a , h light/dark cycle at a temperature of, u00b0C and humidity of, %. Both male and female mice were used in the ADMSC isolation, while only male mice . . .
  

   

  

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