HIGHLIGHTS
- who: Xinye Qian from the Fudan University, China have published the article: Nano-Chemotherapy synergize with immune checkpoint inhibitor- A better option?, in the Journal: (JOURNAL)
- how: Showed that the liposomal doxorubicin ccould trigger a strong CD8+ T_cell response without other off-target side effects.
SUMMARY
The failure to attract tumour-reactive T_cells to the tumour could be caused by the lack of appropriate chemokine secretion from the tumor (e_g the down regulation of CXCL9 prevents CD8+ T_cell tumor-infiltration. The activity of immunosuppressive cells is also important for suppressing the . . .
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