HIGHLIGHTS
- who: Eduardo Ruiz-Lu00f3pez from the Center for Functional University of have published the Article: Nanobodies targeting ABCC3 for immunotargeted applications in glioblastoma, in the Journal: Scientific Reports Scientific Reports
- how: Showed that both nanobodies bind whole-length ABCC3 protein in_vitro u00ad(KD=115.3 u00b1 89.95 u00b5M for NbA42 and u00adKD=52.58 u00b1 25.79 u00b5M for NbA213).
SUMMARY
Despite studies that have suggested higher ABCC3 expression levels in MGMT methylated patient s amples20, the authors found similar ABCC3 levels of expression independently of the MGMT methylation status . . .
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