HIGHLIGHTS
- who: Pouya Safarzadeh Kozani from the (UNIVERSITY) have published the article: Nanobody-based CAR-T cells for cancer immunotherapy, in the Journal: (JOURNAL) of February/28,/2022
- what: The authors shine a light on the limitations of scFvs as CAR targeting domains, discuss the advantages of nanobodies as alternative CAR targeting domains, and, ultimately, the authors review target antigens against which nanobody-based CAR-Ts have been developed and evaluated for the treatment of various types of neoplasms. This advantage of nanobodies is one of the main reasons for investigating them as an alternative to . . .
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