Nanobody-based rfp-dependent cre recombinase for selective anterograde tracing in rfp-expressing transgenic animals

HIGHLIGHTS

• who: Ayumu Inutsuka from the Department Medical University have published the Article: Nanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals, in the Journal: (JOURNAL)
• what: The authors aimed to construct Cre recombinase dependent on RFPs based on the reported tool named Cre-DOG30. Next the authors aimed to control Cre-DOR activity by using chemical ligands.
• how: Quantitative analyses of luciferase assay data showed that recombinase activity is significantly different between Cre-DORN6C1/CreDORN8C8 + mCherry/tdTomato-NES and Cre-DORN6C1/CreDORN8C8 + nls-mCherry/tdTomato Tukey`s . . .
  

   

  

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