Nanofat lysate ameliorates pain and cartilage degradation of osteoarthritis through activation of tgf- β – smad2/3 signaling of chondrocytes

HIGHLIGHTS

  • who: March et al. from the UCSI, Malaysia have published the research: Nanofat lysate ameliorates pain and cartilage degradation of osteoarthritis through activation of TGF- u03b2 - Smad2/3 signaling of chondrocytes, in the Journal: (JOURNAL)
  • what: Speed to separate the exosomes (Exo) from the rest of the fraction, which was so called total protein (TP) in this study.
  • how: The animal data showed that PWL and TWL values Mankin`s and OARSI scorings and the Col2 expression in cartilage were significantly improved in the NFL-treated OA rats. The molecular data showed that . . .

     

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