Nanog confers resistance to complement-dependent cytotoxicity in immune-edited tumor cells through up-regulating cd59

HIGHLIGHTS

• who: Sung Wook Son from the DepartmentCatholic University have published the research: NANOG confers resistance to complement-dependent cytotoxicity in immune-edited tumor cells through up-regulating CD59, in the Journal: Scientific Reports Scientific Reports
• what: In this respect, this study showed that CD59 was upregulated at the transcriptional level during CTL-mediated immunoediting (Fig 1b).

SUMMARY

Previously, the authors established an immune-edited tumor cell line, CaSki P3 (termed P3), generated from its CTL-susceptible parental cell line, CaSki P0 (termed P0), through three rounds of in_vitro selection by cognate . . .

 



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