Nanostructure-specific x-ray tomography reveals myelin levels, integrity and axon orientations in mouse and human nervous tissue

HIGHLIGHTS

• who: Marios Georgiadis from the Institute for Biomedical Engineering, ETH Zurich, Zurich, SwitzerlandYork University have published the paper: Nanostructure-specific X-ray tomography reveals myelin levels, integrity and axon orientations in mouse and human nervous tissue, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors demonstrate the nanostructural specificity of SAXSTT by separately reconstructing central and peripheral nervous system (CNS/PNS) myelin signals based on their distinct nanostructure periodicities (d CNS 15-17 nm; dPNS 19-20 nm), and quantify alterations in CNS myelin levels and nanostructural integrity in a murine model of dysmyelination . . .
  

   

  

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