Nar breakthrough article a single active_site in the mariner transposase cleaves dna strands of opposite polarity

HIGHLIGHTS

• who: Corentin Claeys, Bouuaert and Ronald, Chalmers from the School of Biomedical Sciences, University of Nottingham, Queen's Medical Centre, Nottingham , UH, UK have published the paper: NAR Breakthrough Article A single active_site in the mariner transposase cleaves DNA strands of opposite polarity, in the Journal: (JOURNAL) of June/03,/2017
• what: The authors characterize complexes involved prior to catalysis which define an asymmetric pathway for transpososome assembly. Using mixtures of wild-type and catalytically inactive transposases the authors show that all the catalytic steps of transposition occur within the context of a dimeric transpososome . . .
  

   

  

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