Native doublet microtubules from tetrahymena thermophila reveal the importance of outer junction proteins

HIGHLIGHTS

  • who: Shintaroh Kubo from the (UNIVERSITY) have published the article: Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins, in the Journal: (JOURNAL) of 30/09/2022
  • what: The authors used cryo-EM to determine the structure of native DMTs from the ciliate Tetrahymena thermophila and a combination of mass spectrometry and artificial_intelligence approaches to identify and model proteins inside the DMT. While TtCFAP77 structure and position suggest that it might be important for the suppression of the C-terminal tails of u03b2-tubulins, the study shows that TtCFAP77 is not . . .

     

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