Native glycosylation and binding of the antidepressant paroxetine in a low-resolution crystal structure of human myeloperoxidase

HIGHLIGHTS

  • who: N-glycan refinement and collaborators from the United Kingdom United Kingdom United Kingdom have published the research work: Native glycosylation and binding of the antidepressant paroxetine in a low-resolution crystal structure of human myeloperoxidase, in the Journal: (JOURNAL)
  • how: Using this crystal_structure the authors obtained an elaborate collection of asparagine-linked glycans at the five N-glycosylation sites Asn323 Asn355 Asn391 Asn498 and Asn729 known from proteomics studies (Van Antwerpen et_al 2010 Reiding et_al 2019 Tjondro et_al 2021). The authors compared the glycosylation characterized in the crystal_structure with the N-glycosylation modelled in . . .

     

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