Natural killer cell therapy potentially enhances the antitumor effects of bevacizumab plus irinotecan in a glioblastoma mouse model

HIGHLIGHTS

  • who: Thi-Anh-Thuy Tran et al. from the University of Bonn, Germany have published the paper: Natural killer cell therapy potentially enhances the antitumor effects of bevacizumab plus irinotecan in a glioblastoma mouse model, in the Journal: (JOURNAL)
  • what: Although the NK cells that were expanded by using K562OX40L-mb-IL-18/IL-21 feeder cells showed cytotoxic effects against GBM cells in_vitro and no therapeutic effects on single treatment with s.c and i.c U87 GBM models, the combination of NK cells with Bev and Iri enhanced cytotoxic effects against GBM cells . . .

     

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