Natural resistance to cancers: a darwinian hypothesis to explain peto ’ s paradox

HIGHLIGHTS

  • who: Roche et_al BMC Cancer et al. from the (UNIVERSITY) have published the paper: Natural resistance to cancers: a Darwinian hypothesis to explain Peto ’ s paradox, in the Journal: (JOURNAL)
  • what: The authors propose that oncogenic or tumor suppressive mechanisms should be increasingly purified or positively selected, respectively, above a given threshold in body mass .

SUMMARY

    One of the challenges to multicellular organisms is the deregulation of the cooperative interactions between component cells that natural selection has taken long periods to produce. Cancer is one large class of such multicellular deregulation . . .

     

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