Near-infrared upconversion multimodal nanoparticles for targeted radionuclide therapy of breast cancer lymphatic metastases

HIGHLIGHTS

  • who: Chuan Zhang and colleagues from the Tongji University School of Medicine, China have published the research work: Near-infrared upconversion multimodal nanoparticles for targeted radionuclide therapy of breast cancer lymphatic metastases, in the Journal: (JOURNAL)
  • what: The authors successfully designed a nanoprobe conjugated trastuzumab based on upconversion nanoparticles, further developed a nanonuclear drug labeled 68Ga or 177Lu, adopted a new imaging and theranostic strategy for lymphatic targeting, to realize the multimodal imaging and theranostics of lymph node metastasis.
  • how: These results showed that the nanoprobe had good targeting performance in metastatic lymph . . .

     

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