Near-native visualization of sars-cov-2 induced membrane remodeling and virion morphogenesis

HIGHLIGHTS

  • who: Tim Bergner and collaborators from the Central Facility for Electron Microscopy, Ulm University, Ulm, Germany have published the paper: Near-Native Visualization of SARS-CoV-2 Induced Membrane Remodeling and Virion Morphogenesis, in the Journal: Viruses 2022, 2786 of /2022/
  • what: The authors show the tethering of virions to the plasma membrane in 3D and that accumulations of virus pArticles lacking spike protein in large vesicles are most likely not a result of defective virion assembly at their membrane. The authors evaluate the potential of HPF-FS room-temperature EM samples to visualize ultrastructures . . .

     

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