Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli

HIGHLIGHTS

• who: Sudhirkumar Yanpallewar from the Neural Development Section, Mouse Cancer Genetics Program, CCR, NCI, Frederick, MD, USAUniversity of have published the Article: Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli, in the Journal: Scientific Reports Scientific Reports
• how: This result is in agreement with the findings of Boase et_al3 reporting a similar 50% reduction of Nedd4-2 protein level in the lung from heterozygous animals. Band intensity was quantified using GeneTools Software (Syngene Bio-imaging). | 632957 | DOI 10.1038/srep32957 Data were analyzed using the Statistical Software (GraphPad Prism USA).

 

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