Nemaline myopathy-related skeletal muscle a -actin (acta1) mutation, asp286gly, prevents proper strong myosin binding and triggers muscle weakness

HIGHLIGHTS

• who: Nemaline Myopathy-Related Skeletal Muscle and colleagues from the Department of Neuroscience, Clinical Neurophysiology, Uppsala University, Uppsala, Sweden, Centre for Medical Research, The University of Western Australia have published the research work: Nemaline Myopathy-Related Skeletal Muscle a -Actin (ACTA1) Mutation, Asp286Gly, Prevents Proper Strong Myosin Binding and Triggers Muscle Weakness, in the Journal: PLOS ONE | www.plosone.org of September/20,/2012
• what: The authors aimed at unraveling these mechanisms using muscles from transgenic mouse model of expressing the Asp286Gly To examine the accuracy of these two hypotheses in this study the authors . . .
  

   

  

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