Neoadjuvant chemotherapy vs upfront surgery for resectable locally advanced oral squamous cell carcinoma: a retrospective single center study

HIGHLIGHTS

  • What: The study aimed to investigate the effect of NAC on locally advanced OSCC and identify prognostic factors varying is different therapies to ultimately guide the optimal selection of future treatment. Numerous clinical trials have demonstrated the efficacy of surgical interventions for early-stage OSCC, with ongoing research focusing on the impact of various surgical techniques and extent of resection on the local recurrence rates and preservation of tissue function in early-stage human papilloma virus (HPV)-negative OSCC . The study was approved by the institutional review board and was conducted in accordance with the principles of . . .

     

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