Nestin prevents mesenchymal stromal cells from apoptosis in lps-induced lung injury via inhibition of unfolded protein response sensor ire1 α

HIGHLIGHTS

• who: Hongmiao Wang and collaborators from the Centre for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China have published the research: Nestin prevents mesenchymal stromal cells from apoptosis in LPS-induced lung injury via inhibition of unfolded protein response sensor IRE1 u03b1, in the Journal: (JOURNAL) of 26/07/2022
• what: The authors demonstrated that (i) Nestin could maintain MSC survival within the lung inflammatory microenvironment; (ii) Nestin could bind to IRE1u03b1 and inhibit ER stress-induced apoptosis under stress . . .
  

   

  

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