Network mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways

HIGHLIGHTS

  • who: Key Messages and colleagues from the C The Author Published by Oxford University Press on behalf of the International Epidemiological AssociationDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK have published the Article: Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways, in the Journal: (JOURNAL)
  • what: The authors use the sem function in Stata 1226 for SEM analyses, estimating parameters by maximum_likelihood.
  • future: Where this is not possible reciprocal Mendelian randomization approaches may provide evidence on the direction of causal effects . . .

     

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