HIGHLIGHTS
- who: Hui Deng from the School of Laboratory have published the research: Network pharmacology and experimental validation to identify the potential mechanism of Hedyotis diffusa Willd against rheumatoid arthritis, in the Journal: Scientific Reports Scientific Reports
- how: The WB result showed that HDW could inhibit the PI3K/AKT pathway by reducing phosphorylation of AKT in MH7A cells (P and amplt 0.05 Fig 7B). Hub targets in the work were verified by RT-qPCR and results showed that RELA TNF and IL6 were up-regulated while IL10 was down-regulated (Fig 7C).
SUMMARY . . .
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