HIGHLIGHTS
SUMMARY
The situation has worsened, creating increased urgency to strengthen mental health systems in most countries (COVID-19 Mental Disorders Collaborators, 2021). Some studies suggest there are medications less effective than a placebo (clomipramine; Cipriani et_al, 2018). A recent review has revealed a lack of randomized doubleblind placebo-controlled trials for anxiety disorders and few studies comparing novel treatments to existing anxiolytic agents, concluding that although some randomized controlled trials for novel agents exist, these trials have largely been negative (Garakani et_al, 2020). Pre-COVID studies have shown that at least one person out of . . .
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