Neuro-oncological ventral antigen 2 regulates splicing of vascular endothelial growth factor receptor 1 and is required for endothelial function

HIGHLIGHTS

• who: Veerle Kremer from the Department of Physiology, The Netherlands Location University of have published the research work: Neuro-oncological Ventral Antigen 2 Regulates Splicing of Vascular Endothelial Growth Factor Receptor 1 and Is Required for Endothelial Function, in the Journal: (JOURNAL) of March/22,/2019
• what: The regulation of FLT1 splicing is not fully known and the authors aim to better understand how splicing of this transcript is regulated. The authors demonstrate that loss of NOVA2 is accompanied by increased sFLT1 expression, while NOVA2 interacts with FLT1 mRNA. In this study, NOVA2 was shown . . .
  

   

  

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