Neurocognitive trajectory and proteomic signature of inherited risk for alzheimer’s disease

HIGHLIGHTS

• who: Manish D. Paranjpe and collaborators from the Editor: Zihuai He, Stanford University, UNITED an independent access committeeThe UK have published the research work: Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimeru2019s disease, in the Journal: (JOURNAL)
• what: Although the authors demonstrate here-and others have demonstrated previously -that it is possible to create a polygenic score for Alzheimer`s disease, the authors urge caution prior to deployment outside of a research setting. The polygenic score developed in this study demonstrated an odds ratio per standard deviation increase of 1.90.
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