HIGHLIGHTS
- who: Lotte D. de Hosson from the Department of Medical Oncology, University Medical Box, RB, The Netherlands have published the article: Neuroendocrine tumours and their microenvironment, in the Journal: (JOURNAL) of December/31,/2014
- what: The study showed that NETs exhibit a ‘cold' tumour microenvironment lacking several characteristics that have recently been associated with a response to checkpoint inhibitor treatment .
- how: The authors investigated the tumour immune microenvironment- in particular the presence of PD-L1 T-cells IDO TDO MMRp and cancer-associated fibroblasts (CAFs)-in tissue from patients with treatment-naive serotonin . . .
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